IVF, Fertility and Infertility Treatment by the London Bridge Fertility, Gynaecology and Genetics Centre
We try to see patients as quickly as possible and, in an ever-changing world, short notice appointments sometimes become available due to postponements and schedule changes. See below:



Call Admissions on 020 7089 1449.
23rd February - (18:00-20:00)
- There will be a presentation on "Infertility - Causes and Cures", followed by refreshments, a Question and Answer session and a chance to meet key members of the Bridge team.

Attendence is free but please reserve with Admissions (020 7089 1449)  Bridge Opening Hours
  08:00 – 18:00 Monday to Friday
  08:00 – 14:00 Saturday and Sunday

Glossary of Terms

Assisted Conception – Glossary of Terms

Here are some of the most commonly-used words, terms and acronyms...

A   B   C   D   E   F   G   H   I   K   L   M   N   O   P   R   S   T   U   V   W   X   Y   Z

 


A

 

Abandoned Cycle:

An IVF cycle cancelled after drug administration has begun and before egg collection.

Abortion:

Pregnancy lost before the fetus can survive independently.

Abortion, Threatened:

Spotting or bleeding that occurs early in pregnancy and which may progress to spontaneous abortion.

Acrosome:

Cap-like structure that surrounds the sperm head and contains enzymes that help penetration of the egg. 

Acrosome Reaction:

Chemical changes that enable a sperm to penetrate an egg. 

ACTH:

A hormone produced by the pituitary gland to stimulate the adrenal glands. Excessive levels may lead to fertility problems.

Adhesion:

Scar tissue occurring in the abdominal cavity, fallopian tubes or inside the uterus which can interfere with transport of the egg and implantation of the embryo in the uterus.

Adrenal Androgens:

Male hormones produced by the adrenal gland which, when found in excess, may lead to fertility problems in both men and women. Excess androgens in the woman may lead to the suppression of LH and FSH production by the pituitary gland.

Adrenal Gland:

A pair of hormone producing glands located above the kidneys.

Agglutination:

Clumping sperm together due to infection, inflammation or antibodies.

AID:

Artificial Insemination by Donor.

AIDS:

Acquired immune-deficiency syndrome; a fatal disease caused by HIV that destroys the immune system’s ability to fight infection.

AIH:

Artifical Insemination by Husband.

Alpha-fetoprotein Test (AFP):

A blood test performed to evaluate the development of the fetus and to look for fetal abnormalities. 

Amenorrhea:

Refers to a woman who has never had a period.

Amenorrhea, Secondary:

A term describing a woman who has menstruated at one time, but who has not had a period for six months or more.

Amnicentesis:

A procedure which is usually carried out around 15-16 weeks of pregnancy. It involves aspirating a small amount of the fluid which surround the baby in the womb. This fluid contains cells from the baby which can then be cultured and tested to determine the baby's chromosome. The procedure is usually performed under ultrasound scan using a fine needle. The risk of causing miscarriage by this procedure is between 0.5 - 1%. The results often take two to three weeks.  

Androgens:

Male sex hormones.

Andrologist:

A doctor or scientist who evaluates male fertility.

Anomaly:

Malformation or abnormality in any part of the baby.

Anorexia Nervosa:

A life-threatening eating disorder involving self-imposed starvation. Severe weight loss and malnutrition from this disorder cause anovulation.

Anovulation:

The failure to ovulate; ovulatory failure.

Antibodies:

Chemicals made by the body to fight or attack foreign substances entering the body which cause infertility when they attack the sperm or fetus.

Antigen:

An antigen is any substance capable of eliciting immune response.

Anti-Mullerian Hormone (AMH):

AMH is a protein which, in humans, is encoded by the AMH gene. AMH is structurally related to inhibin and activin and a member of the transforming growth factor family. It is a dimeric glycoprotein that inhibits the development of the Mullerian ducts in the male embryo.

Antisperm Antibodies:

Antisperm antibodies attach themselves to sperm and inhibit their movement and their ability to fertilise.

Antral Follicle Count:

Transvaginal ultrasound method of combing the resting follicles foun on the ovary at the beginning of a cycle.

Artificial Insemination (AI):

The introduction of sperm in the vagina near the cervix or directly into the uterus with the use of a syringe and used to overcome sexual performance problems, to circumvent sperm antibodies, to maximise the potential of poor semen and for the use of donor sperm.

Artificial Insemination Donor (AID):

Artificial insemination with donor sperm using a fresh donor semen specimen or a thawed frozen specimen.

Artificial Insemination Homologous (AIH):

Artificial insemination with the husband's sperm which is washed and injected directly into the wife's uterus (IAIH). Often used with poor semen or to overcome sperm antibody problems.  

Aspermia:

Absence of semen.

Aspiration Cycle:

An initiated ART cycle in which one or more follicles are punctured and aspirated irrespective of whether or not oocytes are retrieved.

Assisted Hatching:

An in vitro procedure in which the zona pellucida of an embryo (usually at eight-cell stage or a blastocyst) is perforated by chemical, mechanical or laser-assisted methods to assist separation of the blastocyst from the zona pellucida.

Assisted Reproductive Technology (ART):

Procedures employed to achieve conception without sexual intercourse, including IUI, GIFT and ZIFT.

Asthenozoospermia:

Low sperm motility.

Atresia:

Degeneration and resorption of a follicle before it reaches maturity and ruptures.

Azoospermia:

Semen containing no sperm, either because the testicles cannot make sperm or because of a blockage in the reproductive tract.

 

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B

 

Basal Body Temperature (BBT):

Body temperature when taken at its lowest point, usually in the morning can be used to predict ovulation.

Basal Body Temperature, Biphasic:

A basal body temperature pattern consistent with ovulation and the formation of the corpus luteum, which secretes progesterone.

Basal Body Temperature, Monophasic:

An anovulatory basal body temperature pattern where the temperature remains relatively constant throughout the cycle.

Beta hCG Test:

A blood test used to detect very early pregnancies and to evaluate embryo development.

Biochemical Pregnancy:

When the patient’s pregnancy test is positive but no pregnancy is visible on ultrasound scan.

Bicornuate Uterus:

A congenital malformation of the uterus where the upper portion is duplicated.

Biopsy:

The removal of a piece of tissue for microscopic examination. 

Birth Defect:

Structural, functional or developmental abnormalities present at birth or later in life, due to genetic or non-genetic factors acting before birth.

Blastocyst:

An embryo with a fluid-filled blastocele cavity which develops five to six days after fertilization.

Blastocyst Transfer:

The transfer of one or more embryos at the blastocyst stage into the uterine cavity.

Blighted Ovum (anembryonic pregnancy):

Fertilised egg that failed to develop properly after implantation. Gestation sac develops in the absence of an embryo.

Bromocriptine (Parlodel):

An oral medication used to reduce prolactin levels and reduce the size of a pituitary tumour when present.

Bulimia:

An eating disorder characterized by voracious eating followed by forced vomiting. The resulting weight loss and malnutrition may cause anovulation.

Buserelin:

A long-acting GnRH available as a nasal spray and used in IVF. It can also be used to treat fibroid tumours and PMS.

 

 

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C

 

Cancelled Cycle:

A treatment cycle in which ovarian stimulation or monitoring has been carried out with the intent of undergoing fertility treatment but which did not proceed to follicular aspiration or, in the case of a thawed embryo, to transfer.

Capacitation:

A process that sperm undergo during travel through the woman's reproductive tract. Capacitation enables the sperm to penetrate the egg.

Cauterize:

To burn tissue with electrical current or with a laser. Used in surgical procedures to remove adhesions and endometrial implants.

Cervical Cerclage:

A procedure in which a stitch or two is put around the cervix to prevent its opening until removed when a pregnancy is to term.

Cervical Mucus:

A viscous fluid at the opening of the cervix which prevents sperm and bacteria from entering the womb. At mid-cycle and under the influence of estrogen, the mucus becomes thinner, allowing sperm to pass into the womb. See also Cervix

Cervical Smear:

A sample of cervical mucus examined microscopically to assess the presence of estrogen and white blood cells, indicating possible infection.

Cervical Stenosis:

A blockage of the cervical canal due to a congenital defect or complications of surgical procedures.

Cervicitis:

Inflammation of the cervix.

Cervix:

The opening between the uterus and the vagina. The cervix remains closed during pregnancy and dilates during labour to allow the baby to be born.

Cervix, Incompetent:

A weakened cervix, which opens up prematurely during pregnancy and can cause the loss of the fetus.

Chemotherapy:

The use of anticancer drugs to treat or control cancer.

Chlamydia:

A sexually transmitted disease. A common cause of pelvic infection and subsequent tubal damage and infertility.

Chocolate Cyst:

A cyst in the ovary filled with old blood which is usually treated with laparoscopy. 

Chromosomes:

The structures in the cell that carry the genes. The human has forty-six chromosomes, twenty-three female and twenty-three male.

Chronic villus sampling (CVS):

A procedure which involves taking a biopsy from the placenta to test the fetus for genetic abnormalities. It is usually carried out under ultrasound scan at about eleven weeks of pregnancy. The placenta has the same genetic make-up as the baby. There is a 2-3% risk of the procedure causing miscarriage.

Cilia:

Tiny hairlike projections on the inside of the fallopian tubes which move the egg towards the uterus.

Clinical Pregnancy:

Evidence of pregnancy by clinical or ultrasound parameters. It includes ectopic pregnancy. Multiple gestational sacs in one patient are counted as one clinical pregnancy.

Clinical Pregnancy Rate:

The number of clinical pregnancies manually expressed as 100 initiated cycles or embryo transfers. When clinical pregnancy rates are shown, the denominator must be specified.

Clitoris:

The small sex organ of the female which contains large numbers of sensory nerves.

Clomiphene (Clomid, Serophene):

A fertility drug that stimulates ovulation through the release of gonadotropins from the pituitary gland."

Clone:

A group of embryos or individuals that are genetically identical.

Coitus:

Intercourse; the sexual union between a man and a woman.

Conception:

See Fertilization.

Conceptus:

The early products of conception; the embryo and placenta.

Condom Therapy:

Therapy prescribed to reduce the number of sperm antibodies in the woman by using a condom during intercourse for six months or more and by eliminating the woman’s contact with the husband's sperm to reduce antibody levels.

Cone Biopsy:

A surgical procedure used to remove precancerous cells from the cervix.

Congenital:

A defect existing since birth.

Congenital Adrenal Hyperplasia:

A congenital condition characterized by elevated androgens which suppress the pituitary gland and interfere with spermatogenesis or ovulation.

Contraception:

A congenital condition characterized by elevated androgens which suppress the pituitary gland and interfere with spermatogenesis or ovulation.

Contraceptive, Oral:

A medication that prevents ovulation and pregnancy which can make a small percentage of women become anovulatory when they stop taking it. The Pill can also disguise fertility problems – such as irregular cycles or endometriosis.

Controlled Ovarian Hyperstimulation (COH):

Medical treatment to induce the development of multiple ovarian follicles to obtain multiple eggs during follicular aspiration.

Cornua:

The horns of the uterus where the fallopian tubes join the uterine cavity.

Corpus Luteum:

The yellow-pigmented glandular structure that forms from the ovarian follicle following ovulation. The gland produces progesterone, which is responsible for preparing and supporting the uterine lining for implantation.

Cryopreservation:

The freezing and storage of sperm, eggs and embryos.

Cryptorchidism:

Failure of one or both testicles to descend into the scrotum.

Cumulus Oophorus:

The protective layer of cells surrounding the egg.

Cushing's Syndrome:

A condition characterized by an overproduction of adrenal gland secretions causing high blood pressure and water retention and pituitary output of LH and FSH. This results in low sperm production or ovulatory failure.

Cyst:

Sac filled with fluid.

Cystic Fibrosis:

A common genetic disease. If both partners carry the gene, there is a 25% chance that the child will have the disease. This is unpleasant and there is currently no cure. It affects the lungs, bowels, pancreas, sweat glands etc.

Cytokines:

Cytokines are messenger molecules produced by lymphocytes. They communicate with other cells of the immune system and recruit them to fight off infection or reject foreign tissue from the body.

Cytomegalovirus infection:

Infection caused by cytomegalovirus. Primary infection of the mother during pregnancy may result in the death of the fetus or serious generalised disease of the newborn. More commonly, congenital infection follows a benign course though about 10% of affected children may subsequently be mentally retarded.

 Cytotoxic:

Cytotoxic refers to a toxic effect on cells.

 

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D

 

 

D&C (Dilation and Curettage):

A procedure used to dilate the cervical canal and scrape out the lining and contents of the uterus used to diagnose or treat the cause of abnormal bleeding and to terminate an unwanted pregnancy.

Danazol (danocrine):

A medication used to treat endometriosis by suppressing LH and FSH production.

Delivery Rate:

The number of deliveries expressed per 100 initiated cycles, aspiration cycles or embryo transfer cycles including deliveries that resulted in a live birth and/or stillbirth. The delivery of a multiple pregnancy is registered as one delivery.

Diagnostic Laparoscopy:

The insertion of a fibre optic telescope into the abdomen to look for abnormalities of the internal pelvic organs.

Dilator:

An instrument used to enlarge a small opening.

DIPI:

Direct intraperitoneal insemination. This is the injection of washed and prepared sperm into the peritoneal cavity under ultrasound guidance.

Dizygotic:

Derived from two. Dizygotic twins were two separate eggs fertilised by separate sperm.

DNA:

A nucleic acid that carries the genetic information in the cell and is capable of self-replication and synthesis of RNA. DNA consists of two long chains of nucleotides twisted into a double helix and joined by hydrogen bonds.

Donor Insemination:

The insemination of donor sperm into the vagina, the cervix, the womb, the tube or peritoneum.

DOT:

Direct Oocyte (egg) Transfer into the uterus.

Down Regulation:

Suppression of the natural secretion of gonadotropins by using GnRh analogues.

Down’s Syndrome:

A genetic disorder caused by the presence of an extra chromosome 21.

Doxycycline:

An antibiotic that inhibits many of the microorganisms infecting the reproductive tract which is used for treating ureaplasma infections.

Duchenne Muscular Dystrophy:

An inherited sex-linked muscular disease.

Dysfunctional:

Abnormal function. 

Dysmenorrhea:

Painful menstruation which may be a sign of endometriosis.

Dyspareunia:

Painful coitus for either the man or the woman.

 

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E

 

Early Neoneonatal Death:

A death occurring within the first seven days after delivery.

Ectopic Pregnancy:

A pregnancy outside of the uterus, usually in the fallopian tube which cannot be sustained. Methotrexate can be used to dissolve the pregnancy without causing major damage to the tube.

Egg Collection:

A procedure used to obtain eggs from ovarian follicles for use in IVF. The procedure is performed during laparoscopy or by using a long needle and ultrasound to locate the follicle in the ovary.

Egg Donor:

A woman who donates her eggs.

Egg Recipient:

A woman who receives embryos created with donor eggs.

Ejaculate:

The semen and sperm expelled during ejaculation.

Ejaculation:

The physiological process by which the semen is propelled from the testicles, through the reproductive tract and out of the penis.

Ejaculatory Ducts:

A pair of ducts, each formed by the joining of a seminal vesicle with a vas deferens.

Embryo:

The early product of conception.

Embryo Donor:

A couple who donate their spare embryos to either infertile couples or for research purposes.

Embryo Recipient:

A woman who receives one or more embryos into the uterine cavity.

Embryo Transfer

Placing an egg fertilised outside the womb into a woman's uterus or fallopian tube.

Empty Sella Syndrome:

A condition that occurs when spinal fluid leaks into the chamber housing the pituitary gland which may adversely affect the ability to secrete LH and FSH.

Endometrial Biopsy:

A procedure during which a sample of the uterine lining is collected for microscopic analysis to confirm ovulation and the proper preparation of the endometrium by estrogen and progesterone stimulation.

Endometriosis:

The presence of small implants of endometrial tissue outside the uterus in abnormal locations.

Endometrium:

The lining of the uterus which grows and sheds in response to estrogen and progesterone stimulation; the bed of tissue designed to nourish the implanted embryo.

Endorphins:

Natural narcotics manufactured in the brain to reduce sensitivity to pain and stress which may contribute to stress-related fertility problems.

Epididymis:

A tubular organ attached to the testicle where developing sperm complete their maturation.

Epididymitis:

Inflammation of the epididymis.

Erection:

The process during which the erectile tissue of the penis becomes engorged with blood, causing the penis to swell and become rigid.

Estradiol:

The female hormone produced in the ovary which supports the growth of the follicle and the development of the uterine lining. At midcycle the peak estrogen level triggers the release of the LH spike necessary for the release of the ovum from the follicle from the pituitary gland.

Estrogens:

The female sex hormones, a group of hormones that are produced mainly by the ovaries. They are essential for normal sexual developments and for the reproductive system.

 

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F

 

Fallopian Tubes:

The ducts through which eggs travel to the uterus once released from the follicle andthe site at which fertilisation usually occurs.

Female Kallman's Syndrome:

A condition characterised by early sexual development and the inability to produce LH and FSH.

Ferning:

A pattern characteristic of dried cervical mucus viewed on a slide which appears when the mucus has been thinned and prepared by estrogen for the passage of sperm.

Fertility Specialist:

A doctor specialising in the practice of fertility.

Fertility Treatment:

Any method or procedure used to enhance fertility or increase the likelihood of pregnancy, such as ovulation induction treatment, varicocoele repair, and microsurgery to repair damaged fallopian tubes. The goal of fertility treatment is to help couples have a child.

Fertility Workup:

The initial medical examinations and tests performed to diagnose or narrow down the cause of fertility problems.

Fertilisation:

The combining of the genetic material carried by sperm and egg to create an embryo. Normally occurs inside the fallopian tube (in vivo) but also occurs in IVF in a petri dish.

Fetus:

A term used to refer to a baby during the period of gestation between eight weeks and term.

Fibroids:

A benign tumor of the uterine muscle and connective tissue.

Fimbria:

The opening of the fallopian tube near the ovary with fingerlike ends which grasp the ovary and coax the egg into the tube.

Flow cytometry:

A method of sperm sorting used for sex selection. X and Y chromosome bearing sperm are stained with different fluorescent dyes and then can be sorted by colour.

Follicles:

Fluid-filled sacs in the ovary which contain the eggs released at ovulation.

Follicular Fluid:

The fluid inside the follicle that cushions and nourishes the ovum.

Follicle Stimulating Hormone (FSH):

A pituitary hormone that stimulates spermatogenesis and follicular development. In the man FSH stimulates the Sertoli cells in the testicles and supports sperm production. In the woman FSH stimulates the growth of the ovarian follicle.

Follicular Phase:

The pre-ovulatory portion of a woman's cycle during which a follicle grows and high levels of estrogen cause the lining of the uterus to proliferate. Normally takes between 12 and 14 days.

Frigidity:

The inability to become sexually aroused.

FSH:

Follicle stimulating hormone is secreted by the pituitary gland. It stimulates the growth of follicles in the female and sperm production in the male.

Full-term Birth:

A birth that takes place at 37 or more completed weeks of gestational age. 

Fundus:

The upper region of the uterus. The fallopian tube opens into the opposite corners of the fundus.

 

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G

 

Galactorrhoea:

Abnormal milk secretion from the breasts.

Gamete:

A reproductive cell:Sperm in men, the egg in women.

Gamete Intrafallopian Transfer (GIFT):

A technique that may be used in lieu of IVF for women with patent tubes. After egg retrieval the eggs are mixed with the husband's sperm and then injected through the fimbria into the woman's fallopian tubes for IVF.

Gene:

The unit of inheritance. Everyone inherits two copies of each gene. One from the father, one from the mother.

Genome:

The basic sets of genes in a chromosome.

Genitals:

The external sex organs, as the labia and clitoris in the woman and the penis and testicles in the man. Also called genitalia.

Germ Cell:

In the male the testicular cell that divides to produce immature sperm cells; in the woman the ovarian cell that divides to form the egg (ovum). The male germ cell remains intact throughout the man's reproductive life; the woman uses up her germ cells at the rate of about one thousand per menstrual cycle, although usually only one egg matures each cycle.

Gestational Carrier:

The age of an embryo or fetus calculated by adding 2 weeks to the number of completed weeks since fertilization.

Gestational Sac:

A fluid-filled structure containing an embryo that develops early in pregnancy usually within the uterus.

GIFT:

Gamete Intra-Fallopian Transfer.

GnRh:

Gonadotrophin-releasing hormone, a hormone secreted by the hypothalamus. It stimulates the pituitary gland to release FSH and LH. GnRh preparation are produced synthetically.

Gonadotropins:

The Follicle Stimulating Hormone (FSH) and Lutenizing Hormone (LH) which control reproductive function.

Gonadotropin Releasing Hormone (GnRH):

A substance secreted by the hypothalamus which enables the pituitary to secrete LH and FSH, which stimulate the gonads.

Gonad:

The gland that makes reproductive cells and sex hormones i.e. the testicles, which make sperm and testosterone, and the ovaries, which make eggs (ova) and estrogen.

Gonal F:

A recombinant human follicular stimulating hormone, known as a ‘fertility drug’.

Gonorrhea:

An infection that is usually asymptomatic and may cause tubal blockage, impair sperm and prevent pregnancy.

 

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H

 

Habitual Abortion:

Repeat miscarriages.

Haemophilia:

A sex-linked inherited blood disease found almost exclusively in men. It is characterised by delayed blood clotting and difficulty in controlling haemorrhage, even after minor injury.

Hatching:

The process that precedes implantation by which an embryo at the blastocyst stage separates from the zona pellucida.

Hepatitis B and C:

Viruses that may be transmitted sexually or by blood and can cause infection of the liver which can lead to jaundice or liver failure.

Hereditary:

A disease transmitted from one’s ancestors.

Heterozygous:

Having two different alleles of a particular gene.

HFEA:

Human Fertilisation and Embryology Authority.

Hirsutism:

Abnormal or excessive hair growth in the body and face.

HIV:

The Human Immuno-deficiency Virus (HIV) is a virus that causes Acquired Immuno Deficiency Syndrome (AIDS).

Homozygous:

Having two of the same alleles of a particular gene.

Hormones:

Chemical substances secreted by endocrine glands, to regulate activities of certain cells and organs.

Host Uterus:

A couple's embryo is transferred to another woman who carries the pregnancy to term and returns the baby to the genetic parents immediately after birth (see Surrogate).

Hostile Mucus:

Cervical mucus that impedes the natural progress of sperm through the cervical canal.

HRT:

Hormone Replacement Treatment.

Human Chorionic Gonadotropin (HCG):

The hormone produced in early pregnancy which keeps the corpus luteum producing progesterone. Also used to trigger ovulation and to stimulate testosterone production.

Human Menopausal Gonadotropin (HMG):

A combination of FSH and LH, which is extracted from the urine of post-menopausal women and used to induce ovulation in fertility treatment.

Humegon:

The lutenizing and follicle-stimulating hormones recovered from the urine of post-menopausal women. Used to stimulate multiple ovulation in fertility treatment.

Huntongton’s Disease:

An inherited sex-linked nervous disease that develops in adulthood and leads to a state of detiorated mentality.

Hyperprolactinemia:

A condition in which the pituitary gland secretes too much prolactin. Prolactin can suppress LH and FSH production, reduce sex drive in the man, and directly suppress ovarian function in the woman.

Hyperthyroidism:

Overproduction of thyroid hormone by the thyroid gland which reduces estrogen levels too rapidly and interferes with ovulation.

Hypoestrogenic:

Having lower than normal levels of estrogen.

Hypogonadotropic Hypopituitarism:

A spectrum of diseases resulting in low pituitary gland output of LH and FSH. Men with this disorder have low sperm counts. Women do not ovulate.

Hyposalpinx:

A blocked, dilated and fluid-filled fallopian tube.

Hypospermatogenesis:

Low sperm production.

Hypothalamus:

A part of the brain located adjacent to and above the pituitary gland which regulates the hormones. In both the man and the woman this tissue secretes GnRH every ninety minutes or so. The pulsatile GnRH enables the pituitary gland to secrete LH and FSH, which stimulate the gonads.

Hypothyroidism:

A condition in which the thyroid gland produces an insufficient amount of thyroid hormone causing a lower sex drive and elevated prolactin in men. Women suffer from elevated prolactin and estrogen, both of which interfere with fertility.

Hysterectomy:

The surgical removal of the uterus. May also include the removal of other reproductive structures such as the fallopian tubes and ovaries.

Hysterosalpingogram (HSG):

An x-ray of the pelvic organs in which a special dye is injected through the cervix into the uterus and fallopian tubes to check for malformations of the uterus and blockage of the fallopian tubes.

Hysteroscopy:

A procedure in which the doctor checks for uterine abnormalities by inserting a fiber-optic device. Minor surgical repairs can be executed during the procedure.

 

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I

 

ICSI:

See also Intracytoplasmic Sperm Injection

Idiopathic:

No causes found.

Immature Sperm (Germinal Cell):

A sperm that has not matured and gained the ability to swim.

Immunoglobulin:

Also called antibodies, produced by B lymphocytes to bind to foreign antigens.

Implantation (Embryo):

The embedding of the embryo into tissue so it can establish contact with the mother's blood supply for nourishment. Implantation usually occurs in the lining of the uterus.

Impotence:

The inability of the man to have an erection and to ejaculate.

Infertility:

Inability of a couple to achieve a pregnancy after one year of unprotected intercourse.

Initiated Cycles:

Treatment cycles in which the woman receives ovarian stimulation or monitoring, irrespective of whether or not follicular aspiration was attempted.

Intracytoplasmic Sperm Injection (ICSI):

A micromanipulation procedure where a single sperm is injected into the egg to enable fertilisation in cases where there are very low sperm counts or non-motile sperm.

Intra Uterine Insemination (IUI):

Insemination of washed and prepared sperm into the uterus.

In Vitro Fertilisation (IVF):

Literally means "in glass." Fertilisation takes place outside the body in a small glass dish.

Infertility:

The inability to conceive after a year of unprotected intercourse or the inability to carry a pregnancy to term.

Inhibin:

A male feedback hormone made in the testicles to regulate FSH production by the pituitary gland.

Inhibin-F (Folliculostatin):

A female feedback hormone made in the ovary to regulate FSH production by the pituitary gland.

IUD (Intrauterine Device):

A device placed into the uterus to prevent pregnancy.

 

 

 

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K

 

Kallman's Syndrome:

A congenital hypothalamus dysfunction which has multiple symptoms including the failure to complete puberty.

Karyotype:

A complete set of human chromosomes.

Karyotyping:

A test performed to analyse chromosomes for the presence of genetic defects.

Klinefelter's Syndrome:

A genetic abnormality characterised by having one Y (male) and two X (female) chromosomes. May cause fertility problems.

 

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L

 

Laparoscope:

A small telescope that can be inserted into a hole in the abdominal wall for viewing the internal organs and to perform a laparoscopy for diagnosis and treatment of a number of fertility problems including endometriosis, abdominal adhesions and polycystic ovaries. Also used in egg retrieval for IVF.

Laparoscopy:

Examination of the pelvic region by using a small telescope called a laparoscope.

Laparotomy:

Major abdominal surgery for the correction of reproductive organ abnormalities such as tubal repairs and the removal of adhesions and fertility restoration.

Leiomyomata:

See Fibroid.

Leydig Cell:

The testicular cell that produces testosterone, the male hormone. The Leydig cell is stimulated by LH from the pituitary gland.

Live Birth:

A birth in which a fetus is delivered with signs of life after complete expulsion or extraction from its mother, beyond 20 completed weeks of gestational age.

Live Birth Delivery Rate:

The number of live birth deliveries expressed per 100 initiated cycles, aspiration cycles or embryo transfer cycles. When delivery rates are given, the denominator (initiated, aspirated, or embryo transfer cycles) must be specified. The delivery of a singleton, twin, or other multiple birth is registered as one delivery.

Liquefaction:

The process by which ejaculate turns from a jelly-like consistency to liquid.

Luteal Phase:

Post-ovulatory phase of a woman's cycle. The corpus luteum produces progesterone, which causes the uterine lining to thicken to support the implantation and growth of the embryo.

Luteal Phase Defect (or deficiency) (LPD):

A condition that occurs when the uterine lining does not develop adequately because of inadequate progesterone stimulation or because of the inability of the uterine lining to respond to progesterone stimulation. LPD may prevent embryonic implantation or cause early miscarriage.

Luteinized Unruptured Follicle (LUF) Syndrome:

A condition in which the follicle develops and changes into the corpus luteum without releasing the egg.

Luteinizing Hormone (LH):

A pituitary hormone that stimulates the gonads. In the man LH is necessary for spermatogenesis (Sertoli cell function) and for the production of testosterone (Leydig cell function). In the woman LH is necessary for the production of estrogen.

Luteinizing Hormone Surge (LH SURGE):

The release of luteinizing hormone (LH) that causes release of a mature egg from the follicle. Ovulation test kits can be used to detect the sudden increase of LH, signaling that ovulation is about to occur (usually within 24-36 hours).

 

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M

 

Malformation Rate:

Includes all structural, functional, genetic and chromosomal abnormalities identified in aborted tissue or diagnosed before or after birth.

MAR:

Mixed Agglutination Reaction, a test to check for the presence or absence of antisperm antibodies.

Masturbation:

Manual stimulation of the penis leading to ejaculation - a technique used to collect semen for analysis and for artificial insemination.

Maturation Arrest:

A testicular condition in which all sperm development halts throughout all testicular tubules. May result in oligospermia or azoospermia.

Meiosis:

The cell division, peculiar to reproductive cells, which allows genetic material to divide in half. Each new cell will contain twenty-three chromosomes. The spermatids and eggs each contain twenty-three chromosomes so, when fertilisation takes place, the baby will have a normal complement of forty-six.

Menarche:

A girl’s first period.

Menogon:

A fertility drug given by injection and consists of FSH and LH.

Menopause:

A condition when the ovaries ran out of eggs. It is usually characterised by absence of periods, hot flushes, sweating and mood changes. The usual age for menopause is around 52.

Menorrhagia:

Heavy or prolonged menstrual flow.

Menstruation:

The cyclical shedding of the uterine lining in response to stimulation from estrogen and progesterone.

Menstrual cycle:

A series of cyclical changes that occur in the female genital system each month.

Metrodine (Pure FSH):

An injectable form of Follicle Stimulating Hormone used to stimulate ovulation.

Micromanipulation:

The use of special micromanipulative technology that allows operative procedures to be performed on the oocyte, sperm or embryo.

Microsurgical Epididymal Sperm Aspiration (MESA):

A procedure in which spermatozoa are obtained from the epididymis by either aspiration or surgical excision.

Miscarriage:

The spontaneous loss of an embryo or fetus from the womb.

Mitosis:

The division of a cell into two identical cells in which all forty-six human chromosomes are duplicated.

Mittleschmerz:

The discomfort felt on one side of the lower abdomen at the time of ovulation.

Monozygotic:

Means single. In monozygotic twins one fertilised egg separates into two identical zygotes.

Morula:

The fertilised egg after a few days of development when it forms a ball of cells.

Motility:

The percentages of all moving sperm in a semen sample.

Multiple Birth:

Birth of more than one baby from a pregnancy.

Mycoplasma:

See Ureaplasma.

Myomectomy:

Surgery performed to remove fibroid tumors.

Myometrium:

The middle muscular layer of the womb.

 

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N

 

Necrozoospermia:

All sperm in the ejaculate are dead.  

Neonatal Death:

A death within 28 days of birth. 

Normegon:

A fertility drug given by injection. It consists of FSH and LH.

Nucleus:

The part of the cell that contains the genetic material DNA.   

 

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O

 

OATS:

Oligoasthenoteratozoospermia (OATS) means low sperm count, low motility and a high proportion of abnormal sperm.

OHSS (Ovarian Hyperstimulation Syndrome):

A potentially life-threatening side-effect of Pergonal ovulation induction treatment which arises when too many follicles develop and hCG is given to release the eggs. May be prevented by withholding the hCG injection.

Oligomenorrhea:

Infrequent menstrual periods.

Oligozoospermia:

A low sperm count (below 20 million) which is low enough to cause a fertility problem.

Oligoovulation:

Infrequent ovulation.

Oocyte Donation:

A fertility treatment procedure performed with third-party oocytes.

Oophorectomy:

The surgical removal of one or both ovaries.

Orgafol:

A fertility drug given by injection. It consists of highly purified FSH.

Orgasm:

The psychological and physical sensation that accompanies sexual climax.

Ovaries:

The two female sex glands which produce eggs and hormones.

Ovarian Cyst:

A fluid-filled sac inside the ovary often found in conjunction with ovulation disorders, tumors of the ovary, and endometriosis.

Ovarian Failure:

The failure of the ovary, diagnosed by elevated FSH in the blood, to respond to FSH stimulation from the pituitary because of damage to or malformation of the ovary.

Ovulation:

The release of the egg from the ovarian follicle.

Ovulation Induction:

Medical treatment performed to initiate ovulation.

Ovulatory Cycle:

A series of cyclical changes that occur within the ovary each month and result in the release of an egg.

Ovulatory Failure (Anovulation):

The failure to ovulate.

Ovum:

The egg; the reproductive cell from the ovary; the female gamete.

Ovum Induction:

The use of fertility drugs to stimulate ovulation if the woman is not producing eggs properly. The aim is to restore physiological ovulation (single follicle). The aim of superovulation is to override and stimulate multiple follicle development.

 

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P

 

Panbypopituitarism:

Total pituitary gland failure. 

Patent:

The condition of being ‘open’, as with tubes that form part of the reproductive organs.

PCT:

Post-coital test, a microscopic examination of a woman’s cervical mucus after intercourse to check the number and motility of sperm in the mucus.

Pelvic Inflammatory Disease (PID):

An infection of the pelvic organs that causes severe illness and extreme pain which may lead to tubal blockage and pelvic adhesions.

Penile Implant:

A device surgically inserted into the penis to provide rigidity for intercourse.

Penis:

The male organ that becomes enlarged and erect for the purpose of depositing semen in the woman's vagina.

Pergonal (HMG):

A medication used to replace the pituitary hormones, LH and FSH frequently used with women who do not produce estrogen because of a pituitary gland or hypothalamic malfunction. May also be used with men to stimulate sperm production. 

Pergoveris:

A fertility drug given by injection. It contains 150 IU recombinant FSH and 75 IU recombinant LH.  

Perinatal Death Rate:

The number of stillbirths and first week deaths per 1,000 delivered.  

PESA:

Percutaneous Epididymal Sperm Aspiration. This involves retrieving sperm directly from the epididymis using a needle.      

Petri Dish:

A shallow glass or plastic cylindrical lidded dish that embryologists use to fertilise eggs with sperm and also used by biologists to culture cells. It is named after German bacteriologist, Julius Richard Petri.

Pituitary Gland:

The master gland that is stimulated by the hypothalamus and controls all hormonal functions. Located at the base of the brain just below the hypothalamus, this gland controls many major hormonal factories throughout the body including the gonads, the adrenal glands and the thyroid gland.

Placenta:

The embryonic tissue that invades the uterine wall and provides a mechanism for exchanging the baby's waste products for the mother's nutrients and oxygen. The baby is connected to the placenta by the umbilical cord.

Polar Body:

The discarded genetic material resulting from female germ cell division.

Polycystic Ovaries Syndrome (PCOS):

A condition found in women who don't ovulate, characterised by excessive production of androgens and the presence of cysts in the ovaries. Though PCOS can be without symptoms, some cases include weight gain, acne and excessive hair growth.

Polyp:

A small growth, usually benign, protruding from the endometrium and dangle into the cavity of the womb. It may interfere with embryo implantation by acting like a coil. Polyps are usually removed surgically.

Post Coital Test (PCT):

A microscopic examination of the cervical mucus best performed twelve or more hours after intercourse to determine compatibility between the woman's mucus and the man's semen and used to detect sperm-mucus interaction problems, the presence of sperm antibodies and the quality of the cervical mucus.

Post-testicular System:

The ducts that store and deliver the sperm to the opening of the penis, including the glands that produce seminal fluids.

Preclinical Abortion:

An abortion that takes place before clinical or ultrasound evidence of pregnancy.

Preclinical Pregnancy:

Evidence of conception based only on biochemical data in serum or urine before ultrasound evidence of a gestational sac.

Pregnancy rate per cycle:

The number of pregnancies achieved from every 100 treatment cycle commenced.

Pregnyl:

A fertility drug given by injection and consists of human chorionic gonadotropin.

Preimplantation Genetic Diagnosis (PGD):

The screening of cells from preimplantation embryos for the detection of genetic and/or chromosomal disorders before embryo transfer.

Preimplantation Genetic Screening (PGS):

A technique used to examine the embryo for aneuploidy (wrong number of chromosomes) and only transfer normal embryos.

Preterm Birth:

A birth that takes place after at least 20, but less than 37, completed weeks of gestation. This includes both live births and stillbirths.  

Premature Menopause:

A condition in which menopause occurs before the age of 40. It affects approximately 1% of women. In most cases there is no identifiable cause. The only effective treatment for infertility is IVF with donated eggs.

Premature Ovarian Failure:

A condition where the ovary runs out of follicles before the normal age associated with menopause.

Pretesticular System:

The male hormonal system responsible for stimulating sperm production and the development of male secondary sex characteristics.

Progesterone:

The hormone produced by the corpus luteum during the second half of a woman's cycle. It thickens the lining of the uterus to prepare it to accept implantation of a fertilised egg.

Profasi:

A fertility drug given by injection and consists of human chorionic gonadotropin.

Progesterone:

A hormone secreted by the corpus luteum in the second half of the menstrual cycle to stimulate the endometrium and prepare it for implantation and maintain it should pregnancy occur.  Progesterone is produced in large quantities by the placenta.

Progesterone Withdrawal:

A diagnostic procedure used to analyse menstrual irregularity and amenorrhea – prior to ovulation induction therapy, progesterone withdrawal may be used to induce a menstrual period.

Prolactin:

The hormone that stimulates the production of milk in breastfeeding women – excessive levels when not breastfeeding may result in infertility.

Pronucleate Stage:

An early stage of fertilisation when the sperm and egg pronuclei are visible under the microscope.

Prostaglandin:

A hormone secreted by the uterine lining. It is possible that prostaglandins secreted by active, young endometrial implants may interfere with the reproductive organs by causing muscular contractions or spasms.

Prostap:

A long-acting GnRh agonist drug used to induce pituitary down-regulation.

Prostate Gland:

A gland in the male reproductive system that produces a portion of the semen including a chemical that liquefies the coagulated semen.

Prostatitis:

Inflammation of the prostate gland usually as a result of infection.

Puberty:

The time of life when the body starts to produce adult levels of sex hormones - (estrogen or testosterone) and adult body characteristics develop.

Puregon:

A recombinant follicle stimulating hormone fertility drug.

PZD:

Partial Zona Dissection, a micromanipulation procedure to help sperm penetrate the zona pellucida.

 

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R

 

Radiotherapy:

The use of radiation and radioactive substances to treat cancer.

Recipient:

The woman who receives an oocyte or an embryo from another woman. 

Recto electro-ejaculation:

A technique used to obtain an ejaculate from spinal injured or otherwise impotent men, where a spinal probe is inserted into the rectum to stimulate the seminal vesicles.

Resistant Ovary:

An ovary that cannot respond to FSH stimulation.

Rubella:

Also called ‘German Measles’, it is caused by an infectious virus and is characterised by general rashes and swollen glands. If infection occurs during the first few months of pregnancy, it may cause severe congenital abnormalities.

 

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S

 

Salpingectomy:

Surgical removal of the fallopian tube.

Salpingitis:

Inflammation of the fallopian tubes caused by infection.

Salpingolysis:

Surgery performed to remove adhesions that restrict the movement and function of reproductive organs.

Salpingostomy:

Surgical repair of the fallopian tubes.

Scrotum:

The bag of skin and muscle surrounding the man's testicles.

Secondary Infertility:

The inability of a couple which has successfully achieved pregnancy to achieve another, including couples for whom the pregnancy did not go to term.

Selective Fetal Reduction:

The process in which one or more normal fetus in a normal in a multiple pregnancy are destroyed.

Semen:

The fluid portion of the ejaculate consisting of secretions from the seminal vesicles, prostate gland and several other glands in the male reproductive tract which provides nourishment and protection for the sperm and a medium in which the sperm can travel to the woman's vagina.

Semen Analysis:

A laboratory test used to assess semen quality, sperm quantity, concentration, morphology, and motility.

Semen Viscosity:

The liquid flow or consistency of the semen.

Seminal Fluid (semen):

The milky fluid that is ejaculated at orgasm. It contains fluid from the seminal vesicles, the prostate and the bulbourethral glands, in addition to sperm.

Seminal Plasma:

Fluid in which the sperm is ejaculated.

Seminal Vesicles:

Glands in the male reproductive system which produce much of the semen volume, including fructose for nourishing the sperm.

Seminiferous Tubes:

The testicular tubules in which the sperm mature and move toward the epididymis.

Septate Uterus:

A uterus divided into right and left halves by a wall of tissue (septum). Women with a septate uterus have an increased chance of early pregnancy loss. 

Septum:

A wall that divides a cavity in half, such as the uterine septum. 

Sertoli Cell:

A testicular cell responsible for nurturing the spermatids (immature sperm). Secretes inhibin, a feedback hormone, which regulates FSH production by the pituitary gland.

Sexually Transmitted Disease:

Also known as ‘venereal disease’ – any disease transmitted by sexual intercourse such as gonorrhoea and chlamydia.

Sheehan's Syndrome:

A condition caused by profuse hemorrhage at the time of delivery.

Short Luted Phase:

A condition frequently found with women undergoing ovulation induction treatment in which the corpus luteum deteriorates prematurely, causing the menstrual period to begin approximately ten days (instead of fourteen) after ovulation.

Sonogram (Ultrasound):

Use of high-frequency sound waves to create an image of internal body parts and to detect and count follicle growth in fertility treatment. Also used to detect and monitor pregnancy.

Sperm:

The male reproductive cell that carries the male’s genetic information to the female's egg.

Spermatid:

An immature sperm cell.

Sperm Agglutination:

Sperm clumping caused by antibody reactions or by infection.

Sperm Antibodies:

Antibodies that attack and maim sperm formed by either the man against his own sperm or by the woman against her husband's sperm.

Sperm Bank:

A place where sperm are kept frozen in liquid nitrogen for use in fertility treatment.

Sperm Count:

The number of sperm in the ejaculate and given as the number of sperm per millilitre.

Sperm Capacitation:

The chemical changes in the sperm that increase its ability to penetrate and fertilise and egg.

Sperm Maturation:

A process during which the sperm grow and gain their ability to swim. Sperm take about ninety days to reach maturity.

Sperm Morphology:

A semen analysis factor that indicates the number or percentage of sperm in the sample that appear to have been formed normally.

Sperm Motility:

The ability of sperm to swim. Poor motility means the sperm have a difficult time reaching the egg.

Sperm Penetration:

The ability of a sperm to penetrate the egg so it can deposit the genetic material during fertilisation.

Spermatogenesis:

Sperm production in the testicles.

Spinnbarkeit:

The stretchability of cervical mucus; the stringy quality that occurs at midcycle under the influence of estrogen.

Split Ejaculate:

A method used to concentrate the sperm for insemination; separating the semen into two portions – the first portion, which is rich in sperm and the second which mostly contains seminal fluid.

Stein-Leventhal Disease:

Another name for polycystic ovaries.

Sterilisation:

An irreversible condition that prevents conception.

Stillbirth:

The death of a fetus between the twentieth week of gestation and birth.

Stimulated Cycle:

A treatment cycle in which fertility drugs are used to produce more eggs than usual in the woman’s monthly cycle.

Subfertility:

Term used to describe any impairment of fertility without implying permanent infertility.

Superovulation:

Stimulation of multiple ovulation with fertility drugs; also known as controlled ovarian hyperstimulation (COH).

Surgical Sperm Retrieval:

The retrieval of sperm from the epididymis or testis, this technique must be used in con junction with ICSI as the sperm retrieved by this technique are incapable of fertilisation by themselves.

Surrogate Mother:

A woman who is artificially inseminated and carries to term a baby which will be raised by its genetic father and his partner.

SUZI:

Subzonal insemination – where a single sperm is injected under the zona of an egg.

Swim-up:

The technique for separating sperm based on their ability to swim through a culture medium.

Syphilis:

A venereal disease caused by spirochete. Acquired infection is transmitted by sexual contact. Congenital infection comes from a mother who has been infected during or shortly before pregnancy.

 

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T

 

TESE:

Testicular Sperm Extraction – involves retrieving sperm directly from the testis.

TESA:

Testicular Sperm Aspiration – procedure in which spermatozoa are obtained directly from the testicle either by aspiration or surgical excision of testicular tissue.

Testicular Biopsy:

A minor surgical procedure which takes a small sample of testicular tissue for microscopic examination to diagnose male fertility problems.

Testicular Enzyme Defect:

A congenital enzyme defect that prevents the testes from responding to hormonal stimulation resulting in oligospermia or azoospermia.

Testicular Failure, Primary:

A congenital, developmental, or genetic error resulting in a testicular malformation that prevents sperm production.

Testicular Failure, Secondary:

Acquired testicular damage - for example, from drugs, prolonged exposure to toxic substances or a varicocoele.

Testicular Function:

The ability of the testicles to produce sperm and testosterone. 

Testicular Stress Pattern:

A semen analysis result showing depressed sperm production, poor sperm motility, and poor sperm morphology consistent with secondary testicular failure or illness.

Testis (testicle):

Male gonad which produces both sperm and male hormones.

Testosterone:

The male hormone necessary for spermatogenesis and responsible for the formation of secondary sex characteristics and for supporting the sex drive.

TET:

Tubal Embryo Transfer.

Thyroid Gland:

The endocrine gland in the front of the neck that produces thyroid hormones to regulate the body's metabolism.

Torsion:

The twisting of the testis inside the scrotum, cutting off the blood supply and causing severe damage to the testicle. Torsion of the ovary may also occur in a woman suffering from hyperstimulation, a complication resulting from ovulation induction treatment. 

Triptorelin:

A long-acting GnRh agonist drug to induce pituitary down-regulation.

Trisomy:

The presence of three chromosomes of one type instead of the normal two.

Tubocornual Anastomosis:

Surgery performed to remove a blocked portion of the fallopian tube and to reconnect the tube to the uterus. Tubouterine implantation may also be performed to remove fallopian tube blockage near the uterus and reimplant the tube in the uterus.

Tuboplasty:

Surgical repair of damaged fallopian tube.

Tubotubal Anastomosis:

Surgery performed to remove a diseased portion of the fallopian tube and reconnect the two ends.

Turner's Syndrome:

The most common genetic defect contributing to female fertility problems. The ovaries fail to form and appear as slender threads of atrophic ovarian tissue, referred to as streak ovaries. Karyotyping will reveal that this woman has only one female (X) chromosome instead of two.

 

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U

 

Ultrasound:

A test which uses sound waves to visualise the reproductive organs, for example, to monitor follicular development and to examine the tubes and uterus.

Umbilical Cord:

Two arteries and one vein encased in a gelatinous tube leading from the baby to the placenta which exchange nutrients and oxygen from the mother for waste products from the baby.

Undescended Testicles (Cryptorchidism):

The failure of the testicles to descend from the abdominal cavity into the scrotum by one year of age. If not repaired by age six, may result in permanent fertility loss.

Unicornuate Uterus:

An abnormality in which the uterus is "one sided" and smaller than usual.

Ureaplasma (Mycoplasma):

An infection that may cause the formation of sperm antibodies and an inflammation of the uterine lining, either of which may interfere with implantation of the embryo.

 

Urethra:

The tube that allows urine to pass between the bladder and the outside of the body. In the man this tube also carries semen from the area of the prostate to the outside.

Urologist:

A doctor specialising in the genitourinary tract.

Uterine Septum:

A band of tissue in the midsection of the uterus that divide the normal uterine cavity.

Uterus:

The hollow, muscular organ that houses and nourishes the fetus during pregnancy.

 

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V

 

Vagina:

The canal leading from the cervix to the outside of the woman's body.

Vaginismus:

Vaginal spasm, inability to relax vaginal muscles before or during intercourse.

Vaginitis:

Infections of the vagina which may indicate the presence of pelvic adhesions and tubal blockage from other infections, such as Chlamydia and which may interfere with sperm penetration of the cervical mucus.

Varicocoele:

A dilation of the veins that carry blood out of the scrotum. The resulting swollen vessels surrounding the testicles create a pool of stagnant blood, which elevates the scrotal temperature and is a major cause of male infertility.

Vas Deferens:

One of the tubes through which the sperm move from the testicles (epididymis) toward the seminal vesicles and prostate gland. These tubes are severed during a vasectomy performed for birth control.

Vasectomy:

The surgical separation of the vas a deferens – a procedure used for birth control.

Vasogram:

An x-ray of the vas deferens.

Venereal Disease:

Any infection that can be sexually transmitted, such as chlamydia, gonorrhea, ureaplasma and syphilis. Many of these diseases interfere with fertility.

Virility:

Being able to perform sexually; having male secondary sex characteristics.

Viscosity:

Thickening of the semen.

 

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W

 

Washing of the sperm:

A procedure to remove the seminal fluid from the sperm.

Welfare of the Child:

The social and ethical considerations used when considering the wellbeing of an individual under the age of 18.

 


X

 

X Chromosome:

The congenital, developmental or genetic information in the cell that transmits the information necessary to make a female. All eggs contain one X chromosome, and half of all sperm carry an X chromosome. When two X chromosomes combine, the baby will be a girl.

 


Y

 

Y Chromosome:

The genetic material that transmits the information necessary to make a male. The Y chromosome can be found in one-half of the man's sperm cells. When an X and a Y chromosome combine, the baby will be a boy.

 


Z

 

ZIFT:

     Zygote Intra-fallopian Transfer.

Zona Pellucida:

      The protective coating surrounding the egg.

Zoladex:

A long-acting GnRh agonist drug used to induce down regulation of the pituitary gland.

Zygote:

     A fertilised egg which has not yet divided.

 

 

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The Bridge Centre is licensed by the Human Fertilisation & Embryology Authority to perform IVF, microsurgical fertilisations and treatments using donated eggs and sperm,
to perform Preimplantation Genetic Diagnosis and Screening and to store genetic material.

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